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診療科・部局・センター

感染症科 医師紹介/学会活動・業績



竹末 芳生

感染症対策室長・感染症科部長
所属 感染症科
資格・認定
  • 日本感染症学会感染症専門医
  • 日本外科学会認定医
  • Infection Control Doctor(ICD)

学会活動・業績

1. ガイドライン (過去5年間)

  • 術後感染予防抗菌薬適正使用のための実践ガイドライン (日本化学療法学会/日本外科感染症学会、追補版 2021) 委員長
  • 侵襲性カンジダ症に対するマネジメントのための臨床実践ガイドライン(日本医真菌学会 2021)委員長
  • 抗菌薬TDM臨床実践ガイドライン(日本化学療法学会/日本TDM学会 2022)委員長
  • MRSA感染症の治療ガイドライン(日本化学慮法学会/日本感染症学会 改訂版2019) 副委員長

2. 学会主催 (過去5年間)

  • 第34回日本環境感染症学会学術集会:2019年2月22日~23日 テーマ:皆でAMR (薬剤耐性)時代に臨む
  • 第68回日本化学療法学会学術総会:2020年9月12日~14日 (神戸国際会議場, 神戸ポートピアホテル)、 テーマ:COVID-19との戦いで学んだこと第3波に向けて準備すべきこと:目指せ、わが国で実践する Antimicrobial stewardship

3. 学会理事、監事など

  • MRSAフォーラム代表世話人:2020年~(在任中)
  • 日本嫌気性菌学会:理事 2014年~2期任期満了、監事 2019年~(在任中)
  • 日本環境感染学会理事: 2006年~ 2期任期満了、2012年~ 2期任期満了
  • 日本化学療法学会理事:2006年~ 2期任期満了、2012年~ 2期任期満了、2018年~ 2期任期満了
  • 日本感染症学会;理事 2015年~ 2期任期満了
  • 日本外科感染症学会:理事2005年~2020年(任期満了)
  • 日本医真菌学会:監事 2019年~2期任期満了
  • International Society of Antimicrobial Chemotherapy:Executive committee 2019~2020年

4. 厚生労働省科学研究(過去5年間)

新興・再興感染症に対する革新的医薬品等開発推進研究事業 研究開発課題:「侵襲性酵母感染症の病原性解明と疫学・診断法・制御法の研究」 「侵襲性酵母感染症の診断・治療法の研究開発と薬剤耐性カンジダ症の疫学研究」
  • 2017年4月~2020年3月分担課題:カンジダ血症診療ガイドラインの検証と新しいエビデンスの確立
  • 2020年4月~2023年3月  同上
  • 2023年4月~2026年3月  同上 

5. 成書、編集(過去5年間)

  • 感染症治療のエッセンス & ピットホール 2018 じほう 総監修
  • AST虎の巻「日常の疑問に答える」2020 中外医学社 編者

6. 受賞(過去5年間)

  • 志賀潔・秦佐八郎記念賞 2021年
  • 日本嫌気性菌感染症学会賞 2022年
  • 日本医真菌学会賞 2019年

7. 論文(過去5年間)

(MRSA 15編、外科感染 13編、真菌 10編、抗菌薬適正使用 7編、サーベイランス 7編、ワクチン6編、新型コロナウイルス 4編、眼科4編、新規抗菌薬2編)
★…重要論文
1) Otani N, Shima M, Ueda T, Nakajima K, Takesue Y, Yamamoto T, Okuno T: Changes in the Epidemiology of Rubella: The Influence of Vaccine-Introducing Methods and COVID-19. Vaccines (Basel). 2023 Aug 12;11(8):1358. doi: 10.3390/vaccines11081358.

2) Samura M, Takada K, Hirose N, Kurata T, Nagumo F, Uchida M, Inoue J, Tanikawa K, Enoki Y, Taguchi K, Matsumoto K, Ueda T, Fujimura S, Mikamo H, Takesue Y, Mitsutake K: Comparison of the efficacy and safety of standard- and high-dose daptomycin: A systematic review and meta-analysis. Br J Clin Pharmacol. 2023 Apr;89(4):1291-1303. doi: 10.1111/bcp.15671.

3) Yoshimura A, Ishikawa H, Uchida K, Takesue Y, Mori J, Kinoshita T, Morikawa S, Okamoto F, Sawada T, Ohji M, Kanda T, Takeuchi M, Miki A, Kusuhara S, Ueda T, Ogata N, Sugimoto M, Kondo M, Yoshida S, Ogata T, Kimura K, Mitamura Y, Jujo T, Takagi H, Terasaki H, Sakamoto T, Sugisawa T, Komuku-Yamamoto Y, Gomi F: Risk Factors for Legal Blindness in 237 Japanese Patients with Exogenous Endophthalmitis: A Multicenter Cohort Study from J-CREST. Ocul Immunol Inflamm. 2023 Jan 26:1-9. doi: 10.1080/09273948.2023.2165111.

4) Sugisawa T, Ishikawa H, Uchida K, Takesue Y, Mori J, Kinoshita T, Morikawa S, Okamoto F, Sawada T, Ohji M, Kanda T, Takeuchi M, Miki A, Kusuhara S, Ueda T, Ogata N, Sugimoto M, Kondo M, Yoshida S, Ogata T, Kimura K, Mitamura Y, Jujo T, Takagi H, Terasaki H, Sakamoto T, Komuku Y, Gomi F: Risk Factors for Legal Blindness in 77 Japanese Patients with Endogenous Endophthalmitis: A Multicenter Cohort Study from J-CREST. Ocul Immunol Inflamm. 2023 Sep;31(7):1505-1512. doi: 10.1080/09273948.2022.2112237.

5) ★Ueda T, Takesue Y, Nakajima K, Ichiki K, Ishikawa K, Yamada K, Tsuchida T, Otani N, Takahashi Y, Ishihara M, Takubo S, Iijima K, Ikeuchi H, Uchino M, Kimura T: Correlation between Antimicrobial Resistance and the Hospital-Wide Diverse Use of Broad-Spectrum Antibiotics by the Antimicrobial Stewardship Program in Japan. Pharmaceutics. 2023 Feb 3;15(2):518. doi: 10.3390/pharmaceutics15020518

6) ★Hanai Y, Ueda T, Hamada Y, Oda K, Takahashi Y, Nakajima K, Miyazaki Y, Kiriyama M, Uekusa S, Matsuo K, Matsumoto K, Kimura T, Takesue Y: Optimal timing for therapeutic drug monitoring of voriconazole to prevent adverse effects in Japanese patients. Mycoses. 2023 Aug 16. doi: 10.1111/myc.13639

7) ★Morosawa M, Ueda T, Nakajima K, Inoue T, Toyama M, Ogasiwa H, Doi M, Nozaki Y, Murakami Y, Ishii M, Takesue Y: Comparison of antibiotic use and antibiotic resistance between a community hospital and tertiary care hospital for evaluation of the antimicrobial stewardship program in Japan. PLoS One. 2023 Apr 24;18(4):e0284806. doi: 10.1371/journal.pone.0284806. eCollection 2023

8) ★Murakami Y, Ogashiwa H, Nozaki Y, Ueda T, Nakajima K, Morosawa M, Doi M, Makino M, Takesue Y: Judicious ending of isolation based on reverse transcription-polymerase chain reaction (RT-PCR) cycle threshold only for patients with coronavirus disease 2019 (COVID-19) requiring in-hospital therapy for longer than 20 days after symptom onset. J Infect Chemother. 2023 Aug;29(8):778-782. doi: 10.1016/j.jiac.2023.05.007.

9) ★Hanai Y, Takahashi Y, Niwa T, Mayumi T, Hamada Y, Kimura T, Matsumoto K, Fujii S, Takesue Y: Clinical practice guidelines for therapeutic drug monitoring of teicoplanin: a consensus review by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring. J Antimicrob Chemother. 2022 Mar 31;77(4):869-879. doi: 10.1093/jac/dkab499

10) ★Kazuaki Matsumoto, Kazutaka Oda, Kensuke Shoji, Yuki Hanai, Yoshiko Takahashi, Satoshi Fujii, Yukihiro Hamada, Toshimi Kimura, Toshihiko Mayumi, Takashi Ueda, Kazuhiko Nakajima, Yoshio Takesue: Clinical Practice Guidelines for Therapeutic Drug Monitoring of Vancomycin in the Framework of Model-Informed Precision Dosing: A Consensus Review by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring. Pharmaceutics 2022, 14, 489; https://doi.org/10.3390/pharmaceutics14030489

11) ★Takesue Y, Hanai Y, Oda K, Hamada Y, Ueda T, Mayumi T, Matsumoto K, Fujii S, Takahashi Y, Miyazaki Y, Kimura T; Japanese Antimicrobial Therapeutic Drug Monitoring Guideline Committee: Clinical Practice Guideline for the Therapeutic Drug Monitoring of Voriconazole in Non-Asian and Asian Adult Patients: Consensus Review by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring. Clin Ther. 2022 Dec;44(12):1604-1623. doi: 10.1016/j.clinthera.2022.10.005

12) Samura M, Kitahiro Y, Tashiro S, Moriyama H, Hamamura Y, Takahata I, Kawabe R, Enoki Y, Taguchi K, Takesue Y, Matsumoto K: Efficacy and Safety of Daptomycin versus Vancomycin for Bacteremia Caused by Methicillin-Resistant Staphylococcus aureus with Vancomycin Minimum Inhibitory Concentration > 1 µg/mL: A Systematic Review and Meta-Analysis. Pharmaceutics. 2022 Mar 27;14(4):714. doi: 10.3390/pharmaceutics14040714

13) ★Ogura H, Gohda J, Lu X, Yamamoto M, Takesue Y, Son A, Doi S, Matsushita K, Isobe F, Fukuda Y, Huang TP, Ueno T, Mambo N, Murakami H, Kawaguchi Y, Inoue JI, Shirai K, Yamasaki S, Hirata JI, Ishido S: Dysfunctional Sars-CoV-2-M protein-specific cytotoxic T lymphocytes in patients recovering from severe COVID-19. Nat Commun. 2022 Dec 16;13(1):7063. doi: 10.1038/s41467-022-34655-1

14) Shoji K, Saito J, Nakamura H, Matsumoto K, Oda K, Takesue Y, Miyairi I: Current Aspects of Pediatric Pharmacokinetics and Pharmacodynamics of Antimicrobials in Japan: Importance of the Promotion of Population PK/PD Analysis. Pediatr Infect Dis J. 2022 Oct 1;41(10):e418-e423. doi: 10.1097/INF.0000000000003622

15) Otani N, Nakajima K, Ishikawa K, Ichiki K, Yoda Y, Ueda T, Takesue Y, Yamamoto T, Tanimura S, Shima M, Okuno T: Comparison of the Hemagglutination Inhibition Titers against Influenza Vaccine Strains in Japan from the 2017/2018 to 2021/2022 Seasons Using a Single Set of Serum Samples. Viruses. 2022 Jun 30;14(7):1455. doi: 10.3390/v14071455

16) ★Hasegawa T, Tashiro S, Mihara T, Kon J, Sakurai K, Tanaka Y, Morita T, Enoki Y, Taguchi K, Matsumoto K, Nakajima K, Takesue Y: Efficacy of surgical skin preparation with chlorhexidine in alcohol according to the concentration required to prevent surgical site infection: meta-analysis. BJS Open. 2022 Sep 2;6(5):zrac111. doi: 10.1093/bjsopen/zrac111

17) ★Ueda T, Takesue Y, Nakajima K, Ichiki K, Ishikawa K, Yamada K, Tsuchida T, Otani N, Takahashi Y, Ishihara M, Takubo S, Ikeuchi H, Uchino M, Kimura T, Matsumoto K, Oda K, Kimura T. Validation of Vancomycin Area under the Concentration-Time Curve Estimation by the Bayesian Approach Using One-Point Samples for Predicting Clinical Outcomes in Patients with Methicillin-Resistant Staphylococcus aureus Infections. Antibiotics (Basel). 2022 Jan 13;11(1):96. doi: 10.3390/antibiotics11010096

18) Kuwahara R, Uchino M, Ikeuchi H, Bando T, Sasaki H, Yasuhara M, Kimura K, Goto Y, Horio Y, Minagawa T, Ikeda M, Ueda T, Takesue Y. Effect of Changing Surgical Instruments Before Wound Closure to Prevent Wound Infection in Lower GI Surgery: A Randomized Controlled Trial. Dis Colon Rectum. 2022 Jan 1;65(1):100-107. doi: 10.1097/DCR.0000000000002035.

19) Ueda T, Takesue Y, Nakajima K, Ichiki K, Ishikawa K, Yamada K, Tsuchida T, Otani N, Ide T, Takeda K, Nishi S, Takahashi Y, Ishihara M, Takubo S, Ikeuchi H, Uchino M, Kimura T. Enhanced loading dose of teicoplanin for three days is required to achieve a target trough concentration of 20 μg/mL in patients receiving continuous venovenous haemodiafiltration with a low flow rate. J Infect Chemother. 2022 Feb;28(2):232-237. doi: 10.1016/j.jiac.2021.10.023

20) Shinkawa H, Kubo S, Mikamo H, Matsuda N, Omura K, Okamoto K, Ono S, Obara H, Kobayashi M, Sasaki J, Shimizu J, Sueyoshi S, Yoshida J, Watanabe M, Takesue Y. Survey on the current status of the indication and implementation protocols for bile replacement in patients with external biliary drainage with special reference to infection control. Surg Today. 2022 Oct;52(10):1446-1452. doi: 10.1007/s00595-022-02475-x.

21) Ikeuchi H, Uchino M, Bando T, Horio Y, Kuwahara R, Minagawa T, Goto Y, Kusunoki K, Ikeda M, Beppu N, Takesue Y: Localization of recurrent lesions following ileocolic resection for Crohn's disease. BMC Surg. 2021 Mar 20;21(1):145. doi: 10.1186/s12893-020-00980-9

22) Ishikawa H, Uchida K, Takesue Y, Mori J, Kinoshita T, Morikawa S, Okamoto F, Sawada T, Ohji M, Kanda T, Takeuchi M, Miki A, Kusuhara S, Ueda T, Ogata N, Sugimoto M, Kondo M, Yoshida S, Ogata T, Kimura K, Mitamura Y, Jujo T, Takagi H, Terasaki H, Sakamoto T, Sugisawa T, Komuku Y, Gomi F: Clinical Characteristics and Outcomes in 314 Japanese Patients with Bacterial Endophthalmitis: A Multicenter Cohort Study from J-CREST. Pathogens. 2021 Mar 24;10(4):390. doi: 10.3390/pathogens10040390

23) Nakada-Motokawa N, Miyazaki T, Ueda T, Yamagishi Y, Yamada K, Kawamura H, Kakeya H, Mukae H, Mikamo H, Takesue Y, Kohno S. Modified Pitt bacteremia score for predicting mortality in patients with candidaemia: A multicentre seven-year retrospective study conducted in Japan. Mycoses. 2021 Dec;64(12):1498-1507. doi: 10.1111/myc.13380.

24) Yanagihara K, Kosai K, Mikamo H, Mukae H, Takesue Y, Abe M, Taniguchi K, Petigara T, Kaku M. Serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae associated with invasive pneumococcal disease among adults in Japan. Int J Infect Dis. 2021 Jan;102:260-268. doi: 10.1016/j.ijid.2020.10.017

25) ★Hashimoto N, Kimura T, Hamada Y, Niwa T, Hanai Y, Chuma M, Fujii S, Matsumoto K, Shigemi A, Kawamura H, Takahashi Y, Takesue Y: Candidates for area under the concentration-time curve (AUC)-guided dosing and risk reduction based on analyses of risk factors associated with nephrotoxicity in vancomycin-treated patients. J Glob Antimicrob Resist. 2021 Dec;27:12-19. doi: 10.1016/j.jgar.2021.07.018.

26) ★Ueda T, Takesue Y, Matsumoto T, Tateda K, Kusachi S, Mikamo H, Sato J, Hanaki H, Mizuguchi T, Morikane K, Kobayashi M, Harihara Y, Seki S, Ishida Y, Fukushima R, Hada M, Matsuo Y, Kubo S, Kimura Y, Hata H, Nakajima K, Ohge H, Akagi S, Takeda S, Fukui Y, Suzuki K, Okamoto K, Yanagihara K, Kawamura H: Change in antimicrobial susceptibility of pathogens isolated from surgical site infections over the past decade in Japanese nation-wide surveillance study. J Infect Chemother. 2021 Jul;27(7):931-939. doi:10.1016/j.jiac.2021.03.010.

27) Otani, N.; Nakajima, K.; Ishikawa, K.; Ichiki, K.; Ueda, T.; Takesue, Y; Yamamoto, T.; Tanimura, S.; Shima, M.; Okuno, T. Changes in Cell-Mediated Immunity (IFN-γ and Granzyme B) Following Influenza Vaccination. Viruses 2021, 13, 1137.

28) ★Oda K, Hashiguchi Y, Kimura T, Tsuji Y, Shoji K, Takahashi Y, Matsumoto K, Kawamura H, Saito H, Takesue Y: Performance of Area under the Concentration-Time Curve Estimations of Vancomycin with Limited Sampling by a Newly Developed Web Application. Pharm Res. 2021;38:637-646.

29) Hanai Y, Hamada Y, Kimura T, Matsumoto K, Takahashi Y, Fujii S, Nishizawa K, Miyazaki Y, Takesue Y: Favorable Effects of Voriconazole Trough Concentrations Exceeding 1 mug/mL on Treatment Success and All-Cause Mortality: A Systematic Review and Meta-Analysis. J Fungi (Basel). 2021;7:306.

30) ★Moeko Tsutsuura; Hiromu Moriyama; Nana Kojima; Yuki Mizukami; Sho Tashiro; Sumika Osa; Yuki Enoki; Kazuaki Taguchi; Kazutaka Oda; Satoshi Fujii; Yoshiko Takahashi; Yukihiro Hamada; Toshimi Kimura; Yoshio Takesue; Kazuaki Matsumoto:The monitoring of vancomycin: a systematic review and meta-analyses of area under the concentration-time curve-guided dosing and trough-guided dosing. BMC Infectious Diseases. 2021 Feb 6;21(1):153.

31) ★Hamada Y, Ueda T, Miyazaki Y, Nakajima K, Fukunaga K, Miyazaki T, Nakada-Motokawa N, Nagao M, Kawamura H, Shigemi A, Ebihara F, Kimura T, Ikegame K, Uchino M, Ikeuchi H, Takesue Y: Effects of antifungal stewardship using therapeutic drug monitoring in voriconazole therapy on the prevention and control of hepatotoxicity and visual symptoms: A multicentre study conducted in Japan. Mycoses.2021 ;63(8):779-786.

32) Yuki Hanai, Yoshiko Takahashi, Takashi Niwa, Toshihiko Mayumi, Yukihiro Hamada, Toshimi Kimura, Kazuaki Matsumoto, Satoshi Fujii, Yoshio Takesue: Optimal trough concentration of teicoplanin for the treatment of methicillin-resistant Staphylococcus aureus infection: A systematic review and meta-analysis. J Clin Pharm Ther. 2021 Feb 6. Online ahead of print.

33) Yuki Hanai, Yukihiro Hamada, Toshimi Kimura, Kazuaki Matsumoto, Yoshiko Takahashi, Satoshi Fujii, Kenji Nishizawa, Yoshio Takesue: Optimal trough concentration of voriconazole with therapeutic drug monitoring in children: A systematic review and meta-analysis. J Infect Chemother. 2021; 27:151-160

34) Hiromu Moriyama, Moeko Tsutsuura, Nana Kojima, Yuki Mizukami, Sho Tashiro, Sumika Osa, Yuki Enoki, Kazuaki Taguchi, Kazutaka Oda, Satoshi Fujii, Yoshiko Takahashi, Yukihiro Hamada, Toshimi Kimura, Yoshio Takesue, Kazuaki Matsumoto: The optimal trough-guided monitoring of vancomycin in children: systematic review and meta-analyses. J Infect Chemother. 2021 Feb 6:S1341-321X(21)00027-1. Online ahead of print

35) Tomoyuki Yamada, Satoshi Fujii, Akari Shigemi, Yoshio Takesue: A meta-analysis of the target trough concentration of gentamicin and amikacin for reducing the risk of nephrotoxicity. J Infect Chemother. 2021; 27:256-261.

36) Oda K, Fujii S, Yamamoto T, Mayumi T, Takesue Y: Evaluation of once-daily dosing and target concentrations in therapeutic drug monitoring for arbekacin: A meta-analysis. J Infect Chemother. 2021; 27:26-31.

37) Ueda T, Takesue Y, Nakajima K, Ichiki K, Ishikawa K, Takai Y, Yamada K, Wada Y, Tsuchida T, Otani N, Takahashi Y, Ishihara M, Shibata S, Ikeuchi H, Uchino M, Kimura T. Vancomycin loading dose is associated with increased early clinical response without attainment of initial target trough concentration at a steady state in patients with methicillin-resistant Staphylococcus aureus infections. J Clin Pharm Ther 2020 Aug;45(4):682-690

38) Osa S, Tashiro S, Igarashi Y, Watabe Y, Liu X, Enoki Y, Taguchi K, Mayumi T, Miyazaki Y, Takesue Y, Matsumoto K.: Azoles versus conventional amphotericin B for the treatment of candidemia: a meta-analysis of randomized controlled trials. J Infect Chemother. 2020 Nov;26(11):1232-1236

39) Mori M, N Ikeda, A Taketomi, Y Asahi, Y Takesue, T Orimo, M Ono, T Kuwayama, Se Nakamura, Y Yamada, T Kuroda, K Yuzawa, T Hibi, H Nagano, M Unno, Y Kitagawa: COVID-19: Clinical issues from the Japan Surgical Society. Surg Today 2020 Aug;50(8):794-808

40) Otani N, Shima M, Tanimura S, Ueda T, Ichiki K, Nakajima K, Takesue Y, Honjo K, Okuno T. Sensitivity and specificity of different antibody tests for detecting varicella-zoster virus. J Infect Chemother. 2020 Aug 22:S1341-321

41) Mimura Y, Yahiro M, Masumoto M, Fukui R, Okamoto R, Aichi M, Mihara Y, Ueda T, Takesue Y, Ikawa K, Morikawa N, Kuragano T. The pharmacokinetics of oral metronidazole in patients with metronidazole‐induced encephalopathy undergoing maintenance hemodialysis. Hemodialysis International. First published: 30 July 2020.

42) Mochizuki Y, Ishikawa H, Sato A, Yamada K, Takesue Y, Gomi F. Pasteurella multocida-induced endophthalmitis after a cat scratch. Am J Ophthalmol Case Rep. 2020 Apr 16;18:100711..

43) ★Ueda T, Takesue Y, Nakajima K, Ichiki K, Ishikawa K, Takai Y, Yamada K, Tsuchida T, Otani N, Takahashi Y, Ishihara M, Shibata S, Ikeuchi H, Uchino M, Kimura T. Clinical efficacy and safety in patients treated with teicoplanin with a target trough concentration of 20 μg/mL using a regimen of 12 mg/kg for five doses within the initial 3 days. BMC Pharmacol Toxicol. 2020 Jul 8;21(1):50

44) Tashiro S, Osa S, Igarashi Y, Watabe Y, Liu X, Enoki Y, Taguchi K, Mayumi T, Miyazaki Y, Takesue Y, Matsumoto K.: Echinocandins versus non-echinocandins for the treatment of invasive candidiasis: A meta-analysis of randomized controlled trials. J Infect Chemother. 2020 Nov;26(11):1164-1176

45) ★Yoneda A, Takesue Y, Takahashi Y, Ichiki K, Tsuchida T, Ikeuchi H, Uchino M, Hatano E, Shinohara H, Tomita N. Improvement in Hyperglycemia Prevents Surgical Site Infection Irrespective of Insulin Therapy in Non-diabetic Patients Undergoing Gastrointestinal Surgery. World J Surg. 2020; 44(5):1450-1458. doi: 10.1007/s00268-020-05371-y.

46) Yamashita C, Takesue Y, Matsumoto K, Ikegame K, Enoki Y, Uchino M, Miyazaki T, Izumikawa K, Takada T, Okinaka K, Ueda T, Miyazaki Y, Mayumi T. Echinocandins versus non-echinocandins for empirical antifungal therapy in patients with hematological disease with febrile neutropenia: A systematic review and meta-analysis. J Infect Chemother. 2020; 1341-1321 (20) 30029-5.

47) Yamada K, Ueda T, Nakajima K, Ichiki K, Tsuchida T, Otani N, Takahashi Y, Ikeuchi H, Uchino M, Koshiba M, Takesue Y: Clinical efficacy of teicoplanin in the treatment of bloodstream infection caused by methicillin-resistant coagulase-negative staphylococci. J Infect Chemother. 2020; 26(5):459-464.

48) Hagihara M, Kusachi S, Kato Y, Yamagishi Y, Niitsuma T, Mikamo H, Takesue Y, Sumiyama Y. Current status of post-operative infections due to antimicrobial-resistant bacteria after digestive tract surgery in Japan: Japan Postoperative Infectious Complications Survey in 2015 (JPICS'15). Surgery today 2020;50(1):56-67.

49) Kosai K, Yamagishi Y, Hashinaga K, Nakajima K, Mikamo H, Hiramatsu K, Takesue Y, Yanagihara K. Multicenter surveillance of the epidemiology of gram-negative bacteremia in Japan. J Infect Chemother. 2020 Mar;26(3):193-198.

50) ★Ueda T, Takesue Y, Tokimatsu I, Miyazaki T, Nakada-Motokawa N, Nagao M, Nakajima K, Mikamo H, Yamagishi Y, Kasahara K, Yoshihara S, Ukimura A, Yoshida K, Yoshinaga N, Izumi M, Kakeya H, Yamada K, Kawamura H, Endou K, Yamanaka K, Yoshioka M, Amino K, Ikeuchi H, Uchino M, Miyazaki Y. The incidence of endophthalmitis or macular involvement and the necessity of a routine ophthalmic examination in patients with candidemia. PLoS One. 2019; 14(5): e0216956.

51) Niitsuma T, Kusachi S, Takesue Y, Mikamo H, Asai K, Watanabe M: Current status of postoperative infections after digestive surgery in Japan: The Japan Postoperative Infectious Complications Survey in 2015. Ann Gastroenterol Surg. 2019 Mar 12;3(3):276-284.

52) Otani N, Shima M, Ueda T, Ichiki K, Nakajima K, Takesue Y, Okuno T.: Evaluation of influenza vaccine-induced cell-mediated immunity: Comparison between methods using peripheral blood mononuclear cells and whole blood. Microbiol Immunol. 2019 Jun;63(6):223-228.

53) Takesue Y, Miyata H, Gotoh M, Wakabayashi G, Konno H, Mori M, Kumamaru H, Ueda T, Nakajima K, Uchino M, Seto Y: Risk calculator for predicting postoperative pneumonia after gastroenterological surgery based on a national Japanese database. Ann Gastroenterol Surg. 2019 Apr 22;3(4):405-415

54) Takesue Y, Uchino M, Ikeuchi H, Ueda T, Nakajima K. Is fixed short-course antimicrobial therapy justified for patients who are critically ill with intra-abdominal infections? J Anus Rectum Colon. 2019 Apr 25;3(2):53-59.

55) ★Uchino M, Ikeuchi H, Bando T, Chohno T, Sasaki H, Horio Y, Nakajima K, Takesue Y: Efficacy of Preoperative Oral Antibiotic Prophylaxis for the Prevention of Surgical Site Infections in Patients With Crohn Disease. Ann Surg 2019;269(3):420-426.

56) Uchino M, Ikeuchi H, Bando T, Chohno T, Sasaki H, Horio Y, Kuwahara R, Minagawa T, Goto Y, Ichiki K, Nakajima K, Takahashi Y, Ueda T, Takesue Y: Associations between multiple immunosuppressive treatments before surgery and surgical morbidity in patients with ulcerative colitis during the era of biologics. Int J Colorectal Dis. 2019; 34(4):699-710.

57) Yanagihara K, Matsumoto T, Aoki N, Sato J, Wakamura T, Kiyota H, Tateda K, Hanaki H, Ohsaki Y, Fujiuchi S, Takahashi M, Akiba Y, Masunaga S, Takeuchi K, Takeda H, Miki M, Kumagai T, Takahashi H, Utagawa M, Nishiya H, Kawakami S, Ishigaki S, Kobayasi N, Takasaki J, Mezaki K, Iwata S, Katouno Y, Inose R, Niki Y, Kawana A, Fujikura Y, Kudo M, Hirano T, Yamamoto M, Miyazawa N, Tsukada H, Aso S, Yamamoto Y, Iinuma Y, Mikamo H, Yamagishi Y, Nakamura A, Ohashi M, Kawabata A, Sugaki Y, Seki M, Hamaguchi S, Toyokawa M, Kakeya H, Fujikawa Y, Mitsuno N, Ukimura A, Miyara T, Hayasi M, Mikasa K, Kasahara K, Koizumi A, Korohasi N, Matumoto T, Yosimura Y, Katanami Y, Takesue Y, Wada Y, Sugimoto K, Yamamoto T, Kuwabara M, Doi M, Simizu S, Tokuyasu H, Hino S, Negayama K, Mukae H, Kawanami T, Yatera K, Fujita M, Kadota J, Hiramatsu K, Aoki Y, Magarifuchi H, Oho M, Morinaga Y, Suga M, Muranaka H, Fujita J, Higa F, Tateyama M: Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for clinical microbiology in 2014: General view of the pathogens' antibacterial susceptibility. J Infect Chemother. 2019; 25(9):657-668.

58) Hirayama T, Miyazaki T, Yamagishi Y, Mikamo H, Ueda T, Nakajima K, Takesue Y, Higashi Y, Yamamoto Y, Kimura M, Araoka H, Taniguchi S, Fukuda Y, Matsuo Y, Furutani A, Yamashita K, Takazono T, Saijo T, Shimamura S, Yamamoto K, Imamura Y, Izumikawa K, Yanagihara K, Kohno S, Mukae H. : Clinical and Microbiological Characteristics of Candida guilliermondii and Candida fermentati. Antimicrob Agents Chemother. 2018 May 25;62(6).

59) Takesue Y, Kusachi S, Mikamo H, Sato J, Watanabe A, Kiyota H, Iwata S, Kaku M, Hanaki H, Sumiyama Y, Kitagawa Y, Nakajima K, Ueda T, Uchino M, Mizuguchi T, Ambo Y, Konosu M, Ishibashi K, Matsuda A, Hase K, Harihara Y, Okabayashi K, Seki S, Hara T, Matsui K, Matsuo Y, Kobayashi M, Kubo S, Uchiyama K, Shimizu J, Kawabata R, Ohge H, Akagi S, Oka M, Wakatsuki T, Suzuki K, Okamoto K, Yanagihara K. Antimicrobial susceptibility of common pathogens isolated from postoperative intra-abdominal infections in Japan. J Infect Chemother. 2018; 24(5): 330-340.

60) Otani N, Shima M, Ueda T, Ichiki K, Nakajima K, Takesue Y, Honjo K, Yoshida N, Kawata S, Okuno T. : Relationship between the frequency of influenza vaccination and cell-mediated immunity. J Immunol Methods. 2018 Jul; 458:58-62.

61) Mikamo H, Tateda K, Yanagihara K, Kusachi S, Takesue Y, Miki T, Oizumi Y, Gamo K, Hashimoto A, Toyoshima J, Kato K : Efficacy and safety of fidaxomicin for the treatment of Clostridioides (Clostridium) difficile infection in a randomized, double-blind, comparative Phase III study in Japan.. J Infect Chemother. 2018 Sep;24(9):744-752.

62) Takahashi Y, Takesue Y, Fujiwara M, Tatsumi S, Ichiki K, Fujimoto J, Kimura T : Risk factors for surgical site infection after major hepatobiliary and pancreatic surgery. J Infect Chemother. 2018 Sep;24(9):739-743.

63) Chohno T, Uchino M, Sasaki H, Bando T, Takesue Y, Ikeuchi H. Associations Between the Prognostic Nutritional Index and Morbidity/Mortality During Intestinal Resection in Patients with Ulcerative Colitis. World J Surg. 2018 Jul;42(7):1949-1959.

64) Horio Y, Uchino M, Bando T, Chohno T, Takesue Y, Ikeuchi H. Association between Higher Body Mass Index and Pouch-Related Complications during Restorative Proctocolectomy in Patients with Ulcerative Colitis. Digestion. 2018;98(4):257-262.

65) Kakeya H, Yamada K, Kaneko Y, Yanagihara K, Tateda K, Maesaki S, Takesue Y, Tomono K, Kadota J, Kaku M, Miyazaki Y, Kamei K, Shibuya K, Niki Y, Yoshida M, Sei Y. [National Trends in the Distribution of Candida Species Causing Candidemia in Japan from 2003 to 2014]. Medical Mycology Journal 2018;59(1):E19-E22.

66) ★Ide T, Takesue Y, Ikawa K, Morikawa N, Ueda T, Takahashi Y, Nakajima K, Takeda K, Nishi S. Population pharmacokinetics/pharmacodynamics of linezolid in sepsis patients with and without continuous renal replacement therapy. International journal of antimicrobial agents 2018;51(5):745-751.

67) Mikamo H, Takesue Y, Iwamoto Y, Tanigawa T, Kato M, Tanimura Y, Kohno S. Efficacy, safety and pharmacokinetics of tedizolid versus linezolid in patients with skin and soft tissue infections in Japan - Results of a randomised, multicentre phase 3 study. J Infect Chemother. 2018 Jun;24(6):434-442.

68) Uchino M, Ikeuchi H, Bando T, Sasaki H, Chohno T, Horio Y, Takesue Y: Ostomy creation with fewer sutures using tissue adhesives (cyanoacrylates) in inflammatory bowel disease: a pilot study. Ann R Coll Surg Engl 2018 Mar;100(3):190-193.
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